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Updated: Jul 19, 2026

High-resolution Tandem Mass Spectrometry for Studying Chemical Constituents of Gynura bicolor DC
Published on: February 2, 2024
[Chemical constituents of Knoxia valerianoides]
1Institute of Pharmacology and Toxicology, Academy of Military Medical Sciences, Beijing 100850, China.
Aim:
To study the chemical constituents of Knoxia valerianoides Thorel et Pitard.
Methods:
Chromatographic methods were used for the isolation and purification. Structures were elucidated on the basis of chemical analysis and spectroscopic data.
Results:
Three anthraguinones were isolated from K. valerianoides and identified as 1, 3, 5-trihydroxy-2-methyl-6-methoxyl-anthraguinone (kaoxiadin, I), 1, 3, 6-trihydroxy-5-ethoxylmethyl-anthraguinone (II) and 1, 3-dihydroxy-2-methylanthraguinone (rubiadin, III).
Conclusion:
Compound II is a new anthraguinone constituent.
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