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Updated: Jul 19, 2026

09:53
Role of Diffusion MRI Tractography in Endoscopic Endonasal Skull Base Surgery
Published on: July 5, 2021
[Endoscopic surgery for nasopharyngeal angiofibroma]
Xiang-min Zhang1, Yi-shu Teng, Wei-ping Wen
1Hospital of Otorhinolaryngology, The First Affiliated Hospital of SUN Yat-Sen University, Otorhinolaryngology, Institute of Sun Yat-sen University, Guangzhou 510080, China.
Summary
Transnasal endoscopic surgery effectively treats juvenile nasopharyngeal angiofibroma (JNA), including cases with minimal intracranial extension. This minimally invasive approach shows promising results with low recurrence rates.
Area of Science:
- Otolaryngology
- Neurosurgery
- Endoscopic Surgery
Background:
- Juvenile nasopharyngeal angiofibroma (JNA) is a rare, benign tumor.
- Surgical management of JNA can be challenging due to its location and potential for recurrence.
- Transnasal endoscopic approaches offer a minimally invasive alternative for JNA resection.
Purpose of the Study:
- To evaluate the efficacy and surgical techniques of transnasal endoscopic procedures for treating JNA.
- To assess outcomes based on tumor staging, including intracranial extension.
Main Methods:
- Twenty-one patients with JNA underwent transnasal endoscopic surgery.
- Patients were staged according to intracranial extension (Group A: none, Group B: minimal).
- Surgical outcomes, including blood loss, residual tumor, and recurrence, were evaluated.
Main Results:
- Nineteen patients (Group A) had an average blood loss of 1000 ml with no residual or recurrent tumors.
- Two patients (Group B) with minimal intracranial extension had an average blood loss of 1500 ml.
- One patient in Group B had minimal residual tumor but no progression; the other had no recurrence.
Conclusions:
- Transnasal endoscopic surgery is a viable treatment for JNA confined to the nasal and nasopharyngeal cavities.
- This technique is also effective for JNA with sphenoid, ethmoid, and minimal intracranial invasions.
- The study supports the use of transnasal endoscopic techniques for a range of JNA presentations.
