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Signal Attenuation as a Rat Model of Obsessive Compulsive Disorder
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Disgust and obsessive-compulsive disorder: an update.

David Berle1, Emily S Phillips

  • 1Clinical Psychologist at the Nepean Anxiety Disorders Clinic and Adult Mental Health Rehabilitation Services, Sydney West Area Health Service, Australia. dberle@bigpond.net.au

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Obsessive-compulsive disorder (OCD) shows a moderate link with the emotion of disgust, especially in contamination-based symptoms. Research confirms brain regions involved in disgust processing are active in OCD.

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Area of Science:

  • Psychiatry
  • Neuroscience
  • Psychology

Background:

  • The emotion of disgust has been increasingly investigated for its role in obsessive-compulsive disorder (OCD).
  • Initial research focused on disgust in specific phobias, but its connection to contamination concerns in OCD prompted further study.
  • Understanding this association may offer new insights into OCD's complex nature.

Purpose of the Study:

  • To review the existing literature on the relationship between disgust and obsessive-compulsive disorder (OCD).
  • To summarize findings on disgust sensitivity, recognition, and neuroimaging in OCD patients.
  • To explore the implications for OCD treatment and future research directions.

Main Methods:

  • Literature review of studies investigating disgust sensitivity, recognition, and neuroimaging in OCD.
  • Synthesis of research findings on the association between disgust responses and OCD symptoms.
  • Analysis of neuroimaging data linking disgust processing areas to OCD.

Main Results:

  • A moderate association exists between disgust and OCD symptoms, particularly contamination-based and religious obsessions.
  • Evidence for a specific disgust recognition deficit in OCD patients is currently lacking.
  • Neuroimaging studies support a link between contamination-focused OCD and the insula cortex, a key area for disgust processing.

Conclusions:

  • Disgust plays a significant role in certain OCD presentations, especially those involving contamination.
  • While a recognition deficit is not evident, brain imaging highlights the insula's involvement in disgust-related OCD.
  • Further research and tailored treatments considering the disgust-OCD link are warranted.