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Related Experiment Videos

Pain management in fulminating ulcerative colitis.

Michelle White1, Neil Shah, Keith Lindley

  • 1United Bristol Health Care Trust, Bristol, UK. mcwdoc@doctors.org.uk

Paediatric Anaesthesia
|October 17, 2006
PubMed
Summary

Ketamine analgesia safely and effectively managed severe pain in children with toxic megacolon (a complication of ulcerative colitis). This approach provided relief without adverse effects, offering a vital alternative when opioids are contraindicated.

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Area of Science:

  • Pediatric Gastroenterology
  • Pain Management
  • Critical Care Medicine

Background:

  • Toxic megacolon, a severe complication of ulcerative colitis, presents significant pain management challenges.
  • Traditional analgesics like NSAIDs and opioids pose risks, including exacerbating bleeding and increasing perforation risk.
  • Effective pain control is crucial for pediatric patients with toxic megacolon.

Observation:

  • This study details the use of low-dose ketamine infusion for analgesia in two children experiencing fulminating ulcerative colitis with toxic megacolon.
  • A protocol involving continuous ketamine infusion with nurse-controlled or patient-controlled analgesia boluses was implemented.
  • A literature review on ketamine analgesia in pediatric patients was also conducted.

Findings:

Related Experiment Videos

  • Low-dose ketamine administered via N/PCA with continuous infusion provided satisfactory pain relief.
  • No adverse effects were reported by the pediatric patients receiving ketamine analgesia.
  • Ketamine demonstrated efficacy in managing severe pain associated with toxic megacolon.

    • Implications:

    • Ketamine analgesia is a safe and effective option for pediatric patients with toxic megacolon.
    • This approach offers a viable alternative to opioids, which are contraindicated in this condition.
    • Further research into ketamine's role in pediatric critical care pain management is warranted.