Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Atomic Force Microscopy01:08

Atomic Force Microscopy

Atomic force microscopy (AFM) is a type of scanning probe microscopy that can analyze topographic details of various specimens like ceramics, glass, polymers, and biological samples. AFM offers over 1000 times more resolution than the optical imaging system. Images generated from AFM are three-dimensional surface profiles, offering an advantage over the flat, two-dimensional images from other imaging techniques.
The AFM Probe
The probe is regarded as the heart of any AFM setup and comprises the...

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

<i>In situ</i> hemisynthesis of new <i>meso</i>-substituted dipyrromethanes using natural aldehydes: <i>in vitro</i> anticholinesterase activity and <i>in silico</i> study.

Natural product research·2026
Same author

Detection of Human Bladder Epithelial Cancerous Cells with Atomic Force Microscopy and Machine Learning.

Cells·2025
Same author

Boosting the Performance of a Zero-gap Flow Microbial Fuel Cell by Immobilized Redox Mediators.

ChemPlusChem·2025
Same author

Stochastic circular persistent currents of exciton polaritons.

Scientific reports·2024
Same author

Machine Learning Allows for Distinguishing Precancerous and Cancerous Human Epithelial Cervical Cells Using High-Resolution AFM Imaging of Adhesion Maps.

Cells·2023
Same author

Identification of Geometrical Features of Cell Surface Responsible for Cancer Aggressiveness: Machine Learning Analysis of Atomic Force Microscopy Images of Human Colorectal Epithelial Cells.

Biomedicines·2023

Related Experiment Video

Updated: Jul 19, 2026

Direct Force Measurements of Subcellular Mechanics in Confinement using Optical Tweezers
09:56

Direct Force Measurements of Subcellular Mechanics in Confinement using Optical Tweezers

Published on: August 31, 2021

Optical detection of the Casimir force between macroscopic objects.

Victor Petrov1, Mikhail Petrov, Valeriy Bryksin

  • 1Institute of Applied Physics, Darmstadt University of Tecnology, Hochschulstrasse 6, Darmstadt 64289, Germany. victor.petrov@physik.tu-darmstadt.de

Optics Letters
|October 17, 2006
PubMed
Summary

Scientists optically detected mechanical deformation caused by the Casimir force. Using a holographic interferometer, they measured pellicle deformations from oscillating Casimir forces, matching calculations.

More Related Videos

Dissecting Mechanoenzymatic Properties of Processive Myosins with Ultrafast Force-Clamp Spectroscopy
09:38

Dissecting Mechanoenzymatic Properties of Processive Myosins with Ultrafast Force-Clamp Spectroscopy

Published on: July 1, 2021

Use of Dual Optical Tweezers and Microfluidics for Single-Molecule Studies
06:53

Use of Dual Optical Tweezers and Microfluidics for Single-Molecule Studies

Published on: November 18, 2022

Related Experiment Videos

Last Updated: Jul 19, 2026

Direct Force Measurements of Subcellular Mechanics in Confinement using Optical Tweezers
09:56

Direct Force Measurements of Subcellular Mechanics in Confinement using Optical Tweezers

Published on: August 31, 2021

Dissecting Mechanoenzymatic Properties of Processive Myosins with Ultrafast Force-Clamp Spectroscopy
09:38

Dissecting Mechanoenzymatic Properties of Processive Myosins with Ultrafast Force-Clamp Spectroscopy

Published on: July 1, 2021

Use of Dual Optical Tweezers and Microfluidics for Single-Molecule Studies
06:53

Use of Dual Optical Tweezers and Microfluidics for Single-Molecule Studies

Published on: November 18, 2022

Area of Science:

  • Optics
  • Condensed Matter Physics
  • Nanotechnology

Background:

  • The Casimir force, a quantum mechanical effect, arises from vacuum fluctuations and influences nanoscale objects.
  • Measuring the Casimir force and its effects on macroscopic objects presents significant experimental challenges.

Purpose of the Study:

  • To optically detect and quantify mechanical deformation of a macroscopic object induced by the Casimir force.
  • To investigate the nonlinear deformations of a thin pellicle under an oscillating Casimir force.

Main Methods:

  • Utilized an adaptive holographic interferometer employing a photorefractive Barium Titanate (BaTiO3:Co) crystal.
  • Measured periodical nonlinear deformations of a thin pellicle subjected to an oscillating Casimir force.

Main Results:

  • Successfully detected optical signals corresponding to mechanical deformation caused by the Casimir force.
  • Observed nonlinear deformations of the pellicle due to the oscillating Casimir force.
  • Achieved reasonable agreement between experimentally measured and theoretically calculated values for the Casimir force harmonics.

Conclusions:

  • The study demonstrates the feasibility of optically detecting Casimir force-induced mechanical deformations in macroscopic systems.
  • The results validate theoretical models describing the Casimir force and its mechanical effects.