[Lobular idiopathic granulomatos mastitis. About 10 cases]

Area of Science:

• Medicine
• Pathology
• Oncology

Background:

• Granulomatous mastitis is a rare, benign breast disease.
• Its etiology is often unclear, with autoimmune factors suspected.
• Diagnosis can be challenging due to potential misinterpretation as malignancy.

Purpose of the Study:

• To review cases of granulomatous mastitis.
• To analyze clinical, mammographic, and histopathological findings.
• To evaluate treatment outcomes and discuss pathogenesis.

Main Methods:

• Retrospective analysis of 10 granulomatous mastitis cases.
• Review of clinical presentations, mammography, and histopathology.
• Assessment of treatment strategies including surgery, antibiotics, and NSAIDs.

Main Results:

• The study included 10 cases (8 women, 2 men) with a mean age of 36.4 years.
• Clinical findings included nodules, inflammatory signs, and nipple discharge.
• Mammography suggested malignancy in 50% of cases; histopathology confirmed diagnosis.
• Treatment involved surgery, with some cases requiring antibiotics and NSAIDs.
• Outcomes included good healing in 4 cases, with one recurrence and fistula.

Conclusions:

• Histopathology is essential for diagnosing granulomatous mastitis.
• Autoimmune pathogenesis is a promising area for further research.
• Management requires a combination of surgical and medical approaches.