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Marjolin's ulcer--a near forgotten entity
B C Tan1, T C Horton, T Sara Ahmad
1Department of Orthopaedic Surgery, University Malaya Medical Centre, Kuala Lumpur, Malaysia.
The Medical Journal of Malaysia
|October 18, 2006
Summary
Squamous cell carcinoma (SCC) can develop in chronic, non-healing ulcers. This case highlights SCC arising in a long-standing hand ulcer, necessitating amputation.
Area of Science:
- Dermatology
- Oncology
- Surgical Pathology
Background:
- Chronic non-healing ulcers pose diagnostic challenges.
- Long-standing skin lesions require vigilant monitoring for malignant transformation.
Observation:
- A 55-year-old male presented with a fungating ulcer on the right hand.
- The ulcer developed at the site of a 40-year-old healed ulcer.
Findings:
- Histopathology confirmed moderately differentiated squamous cell carcinoma (SCC).
- Surgical management involved transradiocarpal amputation with radial flap closure due to extensive tumor infiltration.
Implications:
- This case underscores the importance of considering SCC in chronic, non-healing ulcers.
- Early recognition and biopsy are crucial for timely diagnosis and treatment of cutaneous malignancies.
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