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Published on: October 6, 2015
Primary immunodeficiencies and susceptibility to parasitic infections
1Department of Internal Medicine, University of Cincinnati College of Medicine, Cincinnati, OH 45267-0560, USA. carlos.subauste@uc.edu
Abstract:
Primary immunodeficiencies are important disorders because they typically cause severe illness in affected patients. In addition, these diseases provide a unique glimpse at the underpinnings of the immune system in humans. Susceptibility to infections, including those caused by parasites, is a hallmark of these immune defects. Understanding the association between primary immunodeficiencies and parasitic infections will likely improve our grasp on the mechanisms of defense against these pathogens.
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