Related Experiment Video
Updated: Jul 19, 2026

Modeling Intracerebral Hemorrhage in Mice: Injection of Autologous Blood or Bacterial Collagenase
Published on: September 22, 2012
A patient with wegener granulomatosis and intraventricular hemorrhage
Mitsumasa Kishimoto1, Ken C Arakawa
1University of Hawaii Internal Medicine Residency Program, University of Hawaii John A. Burns School of Medicine, Honolulu, HI, USA. kishimotomi@aol.com
Abstract:
We report a case of intraventricular hemorrhage (IVH) in a 27-year-old man with Wegener granulomatosis (WG), successfully treated with corticosteroids and cyclophosphamide. Neurologic manifestations occur in 22%-54% of patients with WG, with cerebral vasculitis in less than 5%. Only 2 cases of IVH associated with WG have been reported at autopsy. This is the first reported case of in situ IVH associated with WG in a patient who survived. In patients with WG who present with neurologic manifestations, cerebral vasculitis with secondary intracranial hemorrhage should be considered, as these patients are often resistant to immunosuppressive therapies and may present with normal angiograms.
Related Concept Videos
Cerebral Edema ll: Pathophysiology
Hemorrhagic Stroke ll: Pathophysiology
Aneurysm IV: Nursing Management
Increased Intracranial Pressure ll: Pathophysiology
Hemorrhagic Stroke l: Introduction

