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Updated: Jul 19, 2026

Screening of Axonal Degeneration in Carpal Tunnel Syndrome Using Ultrasonography and Nerve Conduction Studies
Published on: January 11, 2019
How valuable is screening for thyroid disease in patients with carpal tunnel syndrome?
1Rheumatic Diseases Unit, Western General Hospital, Edinburgh, Scotland. dr_esuresh@hotmail.com
Background:
It has been suggested that many patients with carpal tunnel syndrome have associated thyroid or other metabolic diseases.
Methods:
206 patients with clinical features suggestive of carpal tunnel syndrome (CTS), including those with known underlying cause of CTS, were screened for thyroid dysfunction. Nerve conduction studies were compatible with a diagnosis of CTS in 136 patients (CTS group).
Results:
We diagnosed only 2 new cases of hypothyroidism (1.5% of patients in the CTS group) and none with hyperthyroidism.
Conclusions:
Thus routine screening of patients with isolated CTS for thyroid function abnormality does not appear to be worthwhile.
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