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Polyarteritis nodosa complicated by catastrophic antiphospholipid syndrome
Bobby Kwanghoon Han1, Kasturi Inaganti, Saleemah Fahmi
1From the *Rheumatic Diseases Division and the †Department of Internal Medicine, University of Texas, Southwestern Medical Center at Dallas, Dallas, Texas.
Abstract:
Polyarteritis nodosa (PAN) is a vasculitis of small- and medium-sized vessels, characterized by vascular aneurysms that can lead to ischemia and infarction. We present the case of a patient with classic polyarteritis nodosa in abdominal organs who additionally demonstrated antitreponemal and antiphospholipid antibodies, resulting in a severe cerebral thrombosis. This case highlights: 1. The potential for false-positive syphilis serology in PAN patients, and 2. The rare coexistence of polyarteritis nodosa and the catastrophic antiphospholipid syndrome.
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