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Endoscopic subureteral injection treatment with calcium hydroxylapatite in primary vesicoureteral reflux

Bilal Eryildirim1, Fatih Tarhan, Uğur Kuyumcuoğlu

  • 1Dr Lütfi Kirdar Kartal Training and Research Hospital, 1, Urology Clinic, Istanbul, Turkey.

International Urology and Nephrology
|October 18, 2006
PubMed

Insights

Subureteral injection of calcium hydroxylapatite effectively treats primary vesicoureteral reflux (VUR) in children. This minimally invasive procedure offers a high success rate for resolving VUR, improving patient outcomes.

Area of Science:

  • Pediatric Urology
  • Minimally Invasive Surgery

Background:

  • Primary vesicoureteral reflux (VUR) affects numerous children.
  • Evaluating novel treatments for VUR is crucial for improving outcomes.

Purpose of the Study:

  • To assess the efficacy of calcium hydroxylapatite subureteral injection for treating primary VUR in pediatric patients.
  • To determine the success rate and safety of this minimally invasive VUR treatment.

Main Methods:

  • A cohort of 25 children with primary VUR underwent subureteral injection of calcium hydroxylapatite.
  • The study included 39 ureteral units with VUR grades II, III, and IV.
  • Treatment involved endoscopic injection of calcium hydroxylapatite.

Main Results:

  • A single injection resolved reflux in 59.0% of ureteral units.
  • A second injection was successful in an additional 12.8% of units.
  • The overall success rate for VUR treatment with calcium hydroxylapatite was 71.8%.

Conclusions:

  • Endoscopic subureteral injection of calcium hydroxylapatite is an effective treatment for primary VUR in children.
  • The procedure is safe and minimally invasive.
  • This technique offers a promising option for managing low-grade VUR.
Abstract

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