Related Experiment Video
Updated: Jul 19, 2026

06:40
Activity-based Training on a Treadmill with Spinal Cord Injured Wistar Rats
Published on: January 16, 2019
Worklife after traumatic spinal cord injury.
Christopher Pflaum1, George McCollister, David J Strauss
1Spectrum Economics, Inc, Overland Park, Kansas, USA.
The Journal of Spinal Cord Medicine
|October 19, 2006
Summary
Predictive models estimate worklife expectancy after spinal cord injury (SCI). Favorable patient factors significantly increase employment likelihood post-SCI, suggesting higher worklife than previously thought.
Area of Science:
- Rehabilitation Medicine
- Health Services Research
- Epidemiology
Background:
- Estimating worklife expectancy after spinal cord injury (SCI) is crucial for individuals and healthcare planning.
- Previous estimates may not fully capture the variability in employment outcomes.
- Understanding factors influencing post-SCI employment is essential for targeted interventions.
Purpose of the Study:
- To develop and validate predictive models for estimating worklife expectancy in individuals with SCI.
- To identify key demographic, injury-related, and socioeconomic factors associated with post-SCI employment.
- To provide a more accurate basis for worklife expectancy estimations in the SCI population.
Main Methods:
- Inception cohort study design utilizing data from the National Spinal Cord Injury Statistical Center database.
- Inclusion of 20,143 individuals enrolled in Model SCI Care Systems across the United States since 1973.
- Logistic regression analysis to identify significant predictors of post-injury employment rates and worklife expectancy.
Main Results:
- Younger age, white race, higher education, marriage, nonviolent injury cause, paraplegia, ASIA D injury, and longer time post-injury were associated with increased employment likelihood.
- Employment at the time of injury and in the prior post-injury year, higher general population employment rates, and lower Social Security Disability Insurance benefits also predicted higher employment.
- Passage of the Americans with Disabilities Act and calendar years thereafter showed a positive association with employment.
Conclusions:
- The likelihood of employment after SCI varies significantly based on individual and contextual factors.
- Favorable patient characteristics and supportive environmental factors can lead to considerably higher worklife expectancy than previously estimated.
- These findings underscore the importance of personalized support and policy interventions to maximize employment opportunities for individuals with SCI.
Related Concept Videos
Spinal Cord Injury ll: Pathophysiology
Spinal cord injury progresses through two interconnected phases: primary injury and secondary injury.Primary InjuryPrimary injury happens at the moment of trauma and involves immediate mechanical damage to the spinal cord.Compression happens when broken vertebrae, herniated discs, or accumulating blood (such as a hematoma) press directly against the spinal cord, distorting its normal shape and function. In cases of contusion, the cord is bruised by a blunt force (like penetrating injuries or...
Secondary Spinal Cord Injury llI: Pathophysiology
Early Ischemia and Ionic ImbalanceWithin minutes of spinal cord injury, a secondary cascade begins, progressing over hours to weeks. Vascular damage reduces blood flow, causing ischemia and mitochondrial dysfunction. ATP depletion leads to ion pump failure, membrane depolarization, sodium influx, potassium efflux, and water accumulation, resulting in cellular swelling. Increased intracellular calcium further disrupts mitochondria and accelerates cellular injury.Excitotoxicity and Neuronal...
Spinal Cord
The spinal cord, a critical component of the central nervous system, extends from the base of the brainstem to the lumbar region of the vertebral column. It is essential for maintaining physical stability and facilitating communication between the brain and peripheral parts of the body.
Traumatic Brain Injury l: Introduction
DefinitionTraumatic brain injury, or TBI, is a disturbance of normal brain function induced by an external mechanical force, such as a direct blow to the head or a penetrating injury. It can affect both brain structure and function, producing a wide range of clinical outcomes. TBI is a heterogeneous condition, meaning its effects may differ based on the type, location, and severity of the injury.Basis of ClassificationTBI is classified based on severity, injury mechanism, or pathophysiology. In...

