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Prevalence of chronic kidney disease in Thai adult population
Anutra Chittinandana1, Worawon Chailimpamontree, Preecha Chaloeiphap
1Renal Division, Department of Medicine, Bhumibol Adulyadej Hospital, Royal Thai Air Force, Bangkok, Thailand. Anutra.rtaf@gmail.com
Insights
Chronic kidney disease (CKD) is prevalent in Thailand
Area of Science:
- Nephrology
- Public Health
- Epidemiology
Background:
- Chronic kidney disease (CKD) poses a significant global health challenge.
- Limited large-scale data exists on pre-dialysis CKD prevalence in Thailand.
- This study addresses the data gap in a specific Thai population.
Purpose of the Study:
- To determine the prevalence of pre-dialysis CKD among Royal Thai Air Force (RTAF) personnel in Bangkok.
- To identify associated risk factors and demographic characteristics of CKD in this cohort.
- To compare the performance of different CKD diagnostic equations.
Main Methods:
- Descriptive analysis of clinical and laboratory data from 15,612 RTAF personnel (2002-2003).
- Exclusion of pilots and aircrew; focus on personnel working in Bangkok.
- CKD staging based on Kidney Disease Outcome Quality Initiative (K/DOQI) guidelines, using Cockcroft-Gault and MDRD formulas.
Main Results:
- CKD prevalence was 9.1% (Cockcroft-Gault) and 4.6% (MDRD).
- Common comorbidities included hypertension (45.8%) and hypercholesterolemia (28.2%).
- CKD patients were older and had higher BMI, blood pressure, and blood sugar.
Conclusions:
- CKD is not uncommon in the studied RTAF population.
- Significant discrepancies exist between Cockcroft-Gault and MDRD equations for GFR estimation in Thais.
- Further evaluation of GFR equations and proteinuria detection methods is recommended for the Thai population.
Objective:
Chronic kidney disease (CKD) is a major public health problem worldwide. Until now, no large-scale data about the prevalence of pre-dialysis CKD has been reported in Thailand.
Material And Method:
The clinical and laboratory data from the ground air force personnel who were routinely checked up during 2002-2003 were collected and descriptively analyzed. The pilots and air crews were excluded. All personnel were working in Bangkok.
Results:
15,612 RTAF personnel completed the annual check up. Eighty-two percent were male. The average age was 45.7 +/- 8 (19-65) years. According to the classification of stages of CKD by Kidney Disease Outcome Quality Initiative (K/DOQI), the prevalence of CKD is 9.1% by Cockcroft Gault formula and 4.6% by Modification of Diet in Renal Disease. Patients with diabetes mellitus, hypertension, hypercholesterolemia and proteinuria were found in 8.2%, 45.8 %, 28.2 % and 1.8% respectively. CKD patients were older had higher body weight, Body Mass Index (BMI), blood pressure and blood sugar than non CKD personnel.
Conclusion:
CKD were not uncommon among RTAF personnel. The Cockcroft-Gault and MDRD equations were different in detecting CKD in the present study. The appropriate equation to determine GFR in Thai population should be evaluated. Low sensitivity of dipstick proteinuria may cause the low prevalence of stage 1 and 2 CKD.
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