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Related Experiment Videos

Chronic ventricular electrograms: do steroid-eluting leads differ from conventional leads?

A Schuchert1, M Hopf, K H Kuck

  • 1Department of Cardiology, University Hospital Eppendorf, Hamburg, West Germany.

Pacing and Clinical Electrophysiology : PACE
|December 1, 1990
PubMed
Summary

Steroid-eluting leads effectively manage chronic pacing thresholds without negatively impacting R wave amplitudes or sensing compared to conventional leads. This study confirms their safety and efficacy in ventricular pacing systems.

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Area of Science:

  • Cardiology and Cardiovascular Devices
  • Biomedical Engineering
  • Electrophysiology

Background:

  • Steroid-eluting leads are designed to lower chronic pacing thresholds.
  • The impact of these leads on R wave amplitudes and sensing requires thorough investigation.

Purpose of the Study:

  • To evaluate if steroid-eluting leads alter acute and chronic R wave amplitudes.
  • To assess the effect of steroid-eluting leads on R wave sensing by the pulse generator.
  • To compare steroid-eluting leads with conventional leads regarding electrogram parameters.

Main Methods:

  • A study involving 31 patients with unipolar ventricular pacemakers.
  • Implantation of two types of steroid-eluting leads (8 mm2 and 5.8 mm2) and two conventional leads.

Related Experiment Videos

  • Measurement of R wave amplitudes, peak-to-peak values, and slew rates at implantation and 1-year follow-up.
  • Evaluation of R wave inhibition at a 5 mV sensitivity setting.

    • Main Results:

    • No significant differences were observed in any measured parameters among the four lead types at implantation.
    • At 1-year follow-up, R wave amplitudes were comparable across all leads, ensuring appropriate sensing.
    • Steroid-eluting leads performed similarly to conventional leads, and smaller electrode surface area did not affect ventricular electrograms.

    Conclusions:

    • Steroid-eluting leads do not adversely affect R wave amplitudes or sensing compared to conventional leads.
    • The use of steroid-eluting leads is a safe and effective option for ventricular pacing.
    • Electrode surface area does not appear to influence ventricular electrogram characteristics in this context.