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Updated: Jul 19, 2026
Online Transcranial Magnetic Stimulation Protocol for Measuring Cortical Physiology Associated with Response Inhibition
Published on: February 8, 2018
Measurement of transcallosal inhibition in traumatic brain injury by transcranial magnetic stimulation
Naoyuki Takeuchi1, Katsunori Ikoma, Takayo Chuma
1Department of Rehabilitation Medicine, Hokkaido University Graduate School of Medicine, Sapporo, Japan. naoyuki@med.hokudai.ac.jp
Primary Objective:
To study whether transcallosal inhibition (TCI) can evaluate the severity of traumatic brain injury (TBI).
Research Design:
Case-control study.
Methods And Procedures:
Twenty patients with a chronic TBI and 20 control subjects were studied. The following transcranial magnetic stimulation parameters were checked; resting motor threshold, central motor latency times, onset latency of TCI, duration of TCI, transcallosal conduction times and amount of TCI. The severity of TBI was evaluated using the Glasgow Coma Scale (GCS).
Main Outcome And Results:
The amount of TCI was significantly lower in the patients than the control subjects (p < 0.001). The amount of TCI was highly correlated with the GCS (r = 0.787, p < 0.001).
Conclusion:
An assessment of TCI was found to be a more sensitive and useful method for an evaluation of the severity of TBI.
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