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![Mizoroki-Heck Cross-coupling Reactions Catalyzed by Dichloro{bis[1,1',1''-(phosphinetriyl)tripiperidine]}palladium Under Mild Reaction Conditions](/_next/image?url=https%3A%2F%2Fcloudfront.jove.com%2FCDNSource%2Fteasers%2F51444.jpg&w=3840&q=50)
Mizoroki-Heck Cross-coupling Reactions Catalyzed by Dichloro{bis[1,1',1''-(phosphinetriyl)tripiperidine]}palladium Under Mild Reaction Conditions
Published on: March 20, 2014
Regioselective Heck arylation of unsaturated alcohols by palladium catalysis in ionic liquid
1Liverpool Center for Materials and Catalysis, Department of Chemistry, University of Liverpool, Liverpool, UK L69 7ZD.
Abstract:
In contrast to almost all of the known examples of Heck arylation of unsaturated alcohols, which yield predominately beta-arylated products, arylation under the Pd-DPPP catalysis in ionic liquid leads preferentially to aryl substitution at the alpha carbon, providing an easy pathway to this valuable class of olefins.
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