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Updated: Jul 19, 2026

Genetic Analysis of Hereditary Transthyretin Ala97Ser Related Amyloidosis
Published on: June 9, 2018
Renal cancer in a patient with Crohn's disease and secondary amyloidosis
Georgios Efstratiadis1, Georgios Tsiaousis, Maria Leontsini
1Department of Nephrology, Aristotelian University of Thessaloniki, Hippokration General Hospital, Thessaloniki, Greece. efstrati@med.auth.gr
Abstract:
Herein we report the case of a patient suffering from renal amyloidosis secondary to Crohn's disease (CD) who presented with anuria and anasarca 8 years after commencement of colchicine treatment. End-stage renal disease was confirmed. Renal imaging prior to hemodialysis showed tumor of the left kidney. Histopathology after nephrectomy revealed secondary amyloidosis as well as the existence of cancer (hypernephroma). We discuss the presence of renal amyloidosis secondary to CD and at the same time renal cancer development, a combination that has not been reported so far, and we emphasize the surprisingly long renal survival of this patient after colchicine treatment.
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