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Updated: Jul 19, 2026
High-resolution Tandem Mass Spectrometry for Studying Chemical Constituents of Gynura bicolor DC
Published on: February 2, 2024
[Studies on the chemical constituents in herb of Ranunculus japonicus]
Wei Zheng1, Chang-xin Zhou, Shui-li Zhang
1Department of Traditional Chinese Medicine and Natural Drug Research, College of Pharmaceutical Sciences, Zhejiang University, Hangdzhou 310031, China.
Objective:
To isolate and determine the chemical constituents from Ranunculus japonicus.
Method:
Compounds were isolated by column chromatography, and identified by MS, NMR data.
Result:
Nine compounds were obtained andelucidated as scoparone (1), tricin (2), protocatechuic acid (3), luteolin (4), anemonin (5), scopoletin (6), 5-hydroxy-6, 7-dimethoxyflavone (7), 5-hydroxy-7, 8-dimethoxyflavone (8), ternatolide (9), respectively.
Conclusion:
Compounds 1-9 were isolated from R. japonicus for the first time while compounds 7, 8 were separated from Ranunculus genus first time.
