Related Experiment Video
Updated: Jul 19, 2026
A Fish-feeding Laboratory Bioassay to Assess the Antipredatory Activity of Secondary Metabolites from the Tissues of Marine Organisms
Published on: January 11, 2015
[Bioactive isomalabaricane triterpenes isolated from marine sponge Rhabdastrella aff. distincta]
1State Key laboratory of Natural and Biomimetic Drugs, Peking University, Beijing 100083, China.
Objective:
To study the chemical constituents of the marine sponge Rhabdastrella aff. distincta.
Method:
Compounds were obtained by normal phase silica gel, Sephadex LH-20, reverse phase chromatogrophy and methylation method. These structures were determined on the basis of IR, MS, NMR spectral analysis.
Result:
Eight compounds were isolated from bioactive CH3Cl fraction and identified as geoditin A (1), geoditin B (2), stellettin A (5), stellettin B (4), stellettin C (3), stellettinE (7), rhabdastrellic acid A (8) and the methyl ester of stellettin E (6).
Conclusion:
All these compounds were obtained from this species for the first time.
