Related Experiment Video
Updated: Jul 19, 2026

Carotid Artery Infusions for Pharmacokinetic and Pharmacodynamic Analysis of Taxanes in Mice
Published on: October 27, 2014
[Study on application of activated carbon in paclitaxel injection]
Li Liu1, Jia-bo Luo, Xue-feng Xing
1Southern Medical University, College of Traditional Chinese Medicine, Key Laboratory of Reasearch of Traditional Chinese Medicine and New Drug, Guangzhou, China.
Objective:
To inspect the effect of activated carbon with different dosage and temperature on quality of paclitaxel injection.
Method:
Determinations in WS1-(X-026)-2001Z-paclitaxel injection were refered to compare the effect of different dosage and temperature for activated carbon on the taxol content, related material, clarity and bacterial endotoxin.
Result:
When used with 0.25% and 35 degrees C, activated carbon will ensure the quality of paclitaxel injection.
Conclusion:
0.25% and 35 degrees C are the best condition when activated carbon is used in paclitaxel injection.
