Related Experiment Video
Updated: Jul 19, 2026
05:14
Comparison of Agreement and Accuracy using Binocular Wavefront Optometer with Autorefractor and Phoropter
Published on: September 16, 2025
Iris-supported phakic lenses (rigid vs foldable version) for treating moderately high myopia: randomized paired eye
Julien Coullet1, José-Luis Guëll, Pierre Fournié
1Ophthalmology Department, Purpan Hospital, Toulouse, France.
American Journal of Ophthalmology
|October 20, 2006
Summary
The Artiflex lens offers faster visual recovery and better uncorrected visual acuity (UCVA) for moderately high myopia compared to the Artisan lens. Further studies with larger sample sizes and longer follow-up are needed to confirm Artiflex lens safety.
Area of Science:
- Ophthalmology
- Refractive Surgery
- Intraocular Lenses
Background:
- Moderately high myopia requires effective correction methods.
- Phakic intraocular lenses (PIOLs) are an option for myopia correction.
- Artisan and Artiflex PIOLs differ in design, potentially impacting outcomes.
Purpose of the Study:
- To compare the refractive performance of Artisan and Artiflex phakic intraocular lenses (PIOLs).
- To evaluate visual acuity and safety outcomes for myopia correction.
Main Methods:
- A randomized pilot study was conducted with 31 patients.
- One eye received an Artisan PIOL, the other an Artiflex PIOL.
- Primary outcome was uncorrected visual acuity (UCVA) at one year; secondary outcomes included safety index and endothelial cell count.
Main Results:
- Artiflex PIOLs showed a significantly higher percentage of eyes with UCVA >20/40 at one year (77.4%) compared to Artisan PIOLs (51.6%).
- Faster visual recovery was observed with Artiflex at one month post-surgery.
- Safety index, best spectacle-corrected visual acuity (BSCVA) changes, and endothelial cell loss were similar between the two PIOLs.
Conclusions:
- The Artiflex lens demonstrates superior UCVA and faster visual recovery for moderately high myopia correction compared to the Artisan lens.
- Larger sample sizes and extended follow-up are recommended to fully establish the safety profile of the Artiflex lens.
Related Concept Videos
01:16Focusing of Light in the Eye
Light rays enter the eye through the cornea, a transparent dome-shaped tissue that is the eye's outermost layer. The cornea bends or refracts, light rays traveling to the pupil. The shape of the cornea determines how much of the light is bent and whether the image will be focused correctly on the retina at the back of the eye. Once the light has passed through both refraction layers, it converges into a single focal point onto a small area. This is where photoreceptors start transforming...
01:28Angle Closure Glaucoma: Treatment
Angle-closure glaucoma, or closed-angle glaucoma, is an eye condition where the iris bulges out and blocks the iridocorneal angle, resulting in a buildup of aqueous humor and increased intraocular pressure. Immediate medical attention is necessary due to the sudden onset of symptoms. The treatment for angle-closure glaucoma includes short-term and long-term approaches. Short-term treatment involves using eye drops like pilocarpine to lower intraocular pressure by increasing aqueous humor...
01:27Open Angle Glaucoma: Treatment
In open-angle glaucoma, the iridocorneal angle remains open, but the trabecular meshwork becomes stiff, slowing down the outflow of aqueous humor. This causes a buildup of aqueous humor in the anterior chamber, leading to a sudden increase in intraocular pressure. The treatment for open-angle glaucoma focuses on reducing the elevated intraocular pressure by either decreasing the secretion of aqueous humor or increasing its outflow.
Drugs such as carbonic anhydrase inhibitors, α2- and...
Drugs such as carbonic anhydrase inhibitors, α2- and...