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Primary cutaneous multifocal CD30+ anaplastic large cell lymphoma
L K Asha1, Daisy Thomas, M P Binitha
1Department of Dermatology and Venereology, Medical College, Calicut, Kerala, India.
Indian Journal of Dermatology, Venereology and Leprology
|October 20, 2006
Abstract:
A 45-year-old male presented with asymptomatic tumors all over the body. The tumors showed no signs of ulceration or regression. There were generalized, nontender, firm to hard enlarged lymph nodes without hepatosplenomegaly. Biopsy and immunophenotyping revealed CD 30+ anaplastic primary cutaneous large cell lymphoma. Primary cutaneous anaplastic large cell lymphoma is characterized by single or grouped reddish-brown tumor nodules, which frequently tend to ulcerate. Secondary involvement of lymph nodes is seen in only 25%. The lesions responded dramatically to chemotherapy, but recurred.