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Updated: Jul 19, 2026

Non-Invasive PET/MR Imaging in an Orthotopic Mouse Model of Hepatocellular Carcinoma
Published on: August 31, 2022
Hepatic imaging in the 21st century
Emil I Cohen1, Eric J Wilck, Robert S Shapiro
1Department of Radiology, Mount Sinai School of Medicine, New York, New York, USA. emil.cohen@mountsinai.org
Liver imaging has advanced significantly with new techniques and contrast agents enhancing diagnostic capabilities. Future imaging will focus more on functional assessment rather than just anatomy.
Area of Science:
- Radiology
- Medical Imaging
- Hepatology
Background:
- Liver imaging modalities including ultrasound, computed tomography, and magnetic resonance imaging (MRI) have seen significant advancements.
- New contrast agents and advanced imaging sequences have improved both anatomic characterization and functional assessment of liver diseases.
Purpose of the Study:
- To review the recent progress in liver imaging techniques.
- To highlight the shift towards functional problem-solving in 21st-century medical imaging.
Main Methods:
- Review of advancements in ultrasound, computed tomography, and MRI for liver imaging.
- Inclusion of new contrast agents and advanced MRI sequences like spectroscopy and diffusion.
- Consideration of workstation developments for image analysis and depiction.
Main Results:
- Enhanced anatomic detail and functional assessment capabilities across all imaging modalities.
- MRI, in particular, benefits from new sequences for microscopic structural analysis.
- Improved image analysis and disease depiction through workstation development.
Conclusions:
- Liver imaging has evolved from providing solely anatomic information to becoming a functional problem-solving tool.
- Continued advancements promise more sophisticated diagnostic capabilities in the future.
- The integration of new technologies is crucial for the progression of liver disease diagnosis and management.
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