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Related Concept Videos

Anatomy of the Adrenal Glands01:17

Anatomy of the Adrenal Glands

The adrenal or supra-renal glands, situated above the kidneys and aligned with the twelfth rib, are paired pyramid-shaped structures crucial for the body's stress response. During stress, these glands secrete hormones vital for adaptive physiological reactions.
These glands possess a distinctive yellow tinge due to the stored cholesterol and fatty acids required for hormone synthesis. They are encased in a fibrous capsule and cushioned by fat.
The adrenal gland comprises two distinct regions...
Adrenal Gland Disorders01:27

Adrenal Gland Disorders

Adrenal gland disorders manifest when the production of adrenal hormones deviates from the norm, resulting in either excessive or insufficient concentrations.
Adrenal insufficiency, characterized by insufficient cortisol and aldosterone production, leads to conditions like Addison's disease. This disorder, affecting the adrenal cortex, exhibits symptoms such as skin bronzing, dehydration, low blood pressure, fatigue, and weight loss. Congenital adrenal hyperplasia, a genetic ailment causing...
External Anatomy of the Kidney01:21

External Anatomy of the Kidney

The kidneys are a pair of bean-shaped organs in the human body that play a critical role in maintaining overall health. They filter out waste products from the blood, regulate blood pressure, maintain electrolyte balance, and stimulate the production of red blood cells.
The kidneys are located in the retroperitoneal space on either side of the vertebral column, protected posteriorly by the 11th and 12th ribs. The right kidney sits slightly lower than the left owing to the presence of the liver...

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Articles linked to this work by shared authors, journal, and citation graph.

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Corrigendum to "International Tailored Chemotherapy Adjuvant (ITACA) trial, a phase III multicenter randomized trial comparing adjuvant pharmacogenomic-driven chemotherapy versus standard adjuvant chemotherapy in completely resected stage II-IIIA non-small-cell lung cancer": [Annals of Oncology 33 (2022) 57-66].

Annals of oncology : official journal of the European Society for Medical Oncology·2022
Same author

International Tailored Chemotherapy Adjuvant (ITACA) trial, a phase III multicenter randomized trial comparing adjuvant pharmacogenomic-driven chemotherapy versus standard adjuvant chemotherapy in completely resected stage II-IIIA non-small-cell lung cancer.

Annals of oncology : official journal of the European Society for Medical Oncology·2021
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Evaluation of nilotinib in advanced GIST previously treated with imatinib and sunitinib.

Cancer chemotherapy and pharmacology·2011
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[Psyche and cancer].

La Clinica terapeutica·2010
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First line chemotherapy in advanced or metastatic NSCLC.

Annals of oncology : official journal of the European Society for Medical Oncology·2006
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Related Experiment Video

Updated: Jul 19, 2026

Endoscopic Endonasal Trans-sphenoidal Approach: Minimally Invasive Surgery for Pituitary Adenomas
07:43

Endoscopic Endonasal Trans-sphenoidal Approach: Minimally Invasive Surgery for Pituitary Adenomas

Published on: January 17, 2018

[Skin adnexal tumors].

C Cauchi1, P Visca, P Donati

  • 1Istituto Nazionale Tumori Regina Elena, Roma, Italia.

La Clinica Terapeutica
|October 21, 2006
PubMed
Summary

Adnexal skin tumors, rare neoplasms from skin appendages, are typically benign but can metastasize. Radical surgery is the primary treatment, with combination chemotherapy showing promise for advanced cases.

Area of Science:

  • Dermatology
  • Oncology
  • Surgical Pathology

Context:

  • Adnexal skin tumors originate from pilosebaceous units and sweat glands.
  • These neoplasms are uncommon, with most presenting as benign lesions.
  • Malignant transformation and metastasis are rare but documented occurrences.

Purpose:

  • To provide a concise overview of adnexal skin tumors.
  • To discuss diagnostic and therapeutic strategies.
  • To highlight prognostic factors and treatment outcomes.

Summary:

  • Diagnosis is histologically confirmed, classifying lesions as benign or malignant.
  • Radical surgery is the preferred treatment; Mohs technique is an option for large tumors.
  • Incomplete excision can lead to local recurrence; metastatic disease carries a poor prognosis.

Related Experiment Videos

Last Updated: Jul 19, 2026

Endoscopic Endonasal Trans-sphenoidal Approach: Minimally Invasive Surgery for Pituitary Adenomas
07:43

Endoscopic Endonasal Trans-sphenoidal Approach: Minimally Invasive Surgery for Pituitary Adenomas

Published on: January 17, 2018

Impact:

  • Establishes histological diagnosis as crucial for adnexal tumor management.
  • Emphasizes surgical intervention as the mainstay of treatment.
  • Suggests combination chemotherapy as a potentially superior option for metastatic adnexal tumors.