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Leishmaniasis

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Updated: Jul 19, 2026

Cutaneous Leishmaniasis in the Dorsal Skin of Hamsters: a Useful Model for the Screening of Antileishmanial Drugs

Cutaneous Leishmaniasis in the Dorsal Skin of Hamsters: a Useful Model for the Screening of Antileishmanial Drugs

Published on: April 21, 2012

Lid leishmaniasis: an atypical clinical presentation.

Arfan-ul-Bari¹, Inam-ul-Haq, Maliha Rani

¹Department of Dermatology, CMH. Muzaffarabad, AJK, Pakistan. albariul@yahoo.com

Journal of the College of Physicians and Surgeons--Pakistan : JCPSP

|October 21, 2006

Summary

Localized cutaneous leishmaniasis (CL) can present unusually on the eyelid, causing significant visual impairment. This case report details successful treatment of extensive eyelid CL with melamine antimonite compound.

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Cutaneous Leishmaniasis in the Dorsal Skin of Hamsters: a Useful Model for the Screening of Antileishmanial Drugs

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Area of Science:

Dermatology
Infectious Diseases
Ophthalmology

Background:

Localized cutaneous leishmaniasis (CL) commonly manifests as nodules or plaques on the face and extremities.
Unusual presentations of CL are documented, highlighting the disease's varied clinical spectrum.
The eyelid is a rare site for sand fly bites and subsequent CL development.

Observation:

An elderly male presented with an extensive CL lesion covering his entire right upper eyelid.
The lesion severely restricted his ability to open his eye, impacting vision.
This case represents a rare instance of CL affecting the ocular region.

Findings:

The patient received treatment with a melamine antimonite compound.
Complete resolution of the cutaneous leishmaniasis lesion was achieved.
Treatment duration was approximately 4 weeks.

Implications:

This case underscores the importance of considering CL in the differential diagnosis of eyelid lesions, even in atypical locations.
Melamine antimonite compounds demonstrate efficacy in treating rare, extensive presentations of cutaneous leishmaniasis.
Further research into the management of ocular CL may be warranted to optimize patient outcomes.