Related Experiment Video
Updated: Jul 19, 2026
Endoscopic Cholesteatoma Surgery
Published on: January 19, 2022
Hexosaminidase as a new potential marker for middle ear cholesteatoma
Ewa Olszewska1, Malgorzata Borzym-Kluczyk, Slawomir Olszewski
1Department of Otolaryngology, Medical University, ul. Sklodowskiej 24 A, 15-274 Bialystok, Poland. ewaolsz@yahoo.com <ewaolsz@yahoo.com>
Objectives:
The study aim was to investigate the activities of hexosaminidase (HEX) in cholesteatoma tissue compared with that in normal skin.
Design And Methods:
The enzyme activities were determined using the Chatterjee et al. method in the modification of Zwierz et al. in cholesteatoma and skin.
Results:
Significantly higher activity of hexosaminidase was observed in cholesteatoma tissue compared with the skin.
Conclusions:
Hex may be considered as a new pathogenetic factor in that destructive lesion.
