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Modifying Levels of Maternal Dietary Folic Acid or Choline to Study the Impact of Deficiencies on Offspring Health Outcomes
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Effects of folinic acid and Vitamin B12 on ethanol-induced developmental toxicity in mouse

Yajun Xu1, Li Li, Zhaofeng Zhang

  • 1Department of Nutrition & Food Hygiene, School of Public Health, Laboratory of Molecular Toxicology & Developmental Molecular Biology, Peking University, Beijing 100083, China.

Toxicology Letters
|October 21, 2006
PubMed

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Teratogenicity01:07

Teratogenicity

The ability of a drug to produce structural deformations and functional abnormalities in the developing embryo or the fetus is called teratogenicity, and the drug producing this effect is known as a teratogen. Teratogenic effects include stillbirth, miscarriage, intrauterine growth restriction, and neurocognitive delay. A teratogen may affect the embryo at different stages of development, which is important in determining the type and extent of the damage. During blastocyst formation, the early...