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Related Experiment Video

Updated: Jul 19, 2026

Micro-dissection of Enamel Organ from Mandibular Incisor of Rats Exposed to Environmental Toxicants

Micro-dissection of Enamel Organ from Mandibular Incisor of Rats Exposed to Environmental Toxicants

Published on: March 29, 2018

Occupational exposure in dentistry and miscarriage.

Marja-Liisa Lindbohm¹, Pekka Ylöstalo, Markku Sallmén

¹Finnish Institute of Occupational Health, Helsinki, Finland. marja-liisa.lindbohm@ttl.fi

Occupational and Environmental Medicine

|October 21, 2006

Summary

Dental workers exposed to mercury amalgam, solvents, and disinfectants showed a slightly increased risk of miscarriage. While no strong associations were found, these occupational exposures warrant further investigation.

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Last Updated: Jul 19, 2026

Micro-dissection of Enamel Organ from Mandibular Incisor of Rats Exposed to Environmental Toxicants

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Published on: March 29, 2018

Long-term Behavioral and Reproductive Consequences of Embryonic Exposure to Low-dose Toxicants

Long-term Behavioral and Reproductive Consequences of Embryonic Exposure to Low-dose Toxicants

Published on: March 6, 2018

Area of Science:

Occupational health
Reproductive toxicology
Environmental medicine

Background:

Limited data exists on reproductive health effects from chemical exposures in dental settings.
Dental professionals face potential exposure to various chemicals, including mercury amalgam, solvents, and disinfectants.

Purpose of the Study:

To assess the risk of miscarriage among women dental workers exposed to specific chemical agents.
Investigate potential links between occupational exposure to acrylate compounds, mercury amalgam, solvents, and disinfectants and miscarriage risk.

Main Methods:

A case-control study involving women dental workers and an unexposed comparison group.
Pregnancy outcomes were obtained from national registers and hospital records.
Occupational exposure was assessed via questionnaires and expert evaluation, with logistic regression used for analysis.

Main Results:

A slightly increased risk of miscarriage was observed with exposure to mercury amalgam (OR 2.0 for moderate exposure).
Elevated risks were also noted for exposure to certain acrylate compounds, organic solvents, and disinfectants.
No strong, consistent dose-response relationships were identified for most chemical exposures.

Conclusions:

A definitive strong association between dental chemical exposures and miscarriage risk was not established.
However, a potential weak association between mercury amalgam, acrylate compounds, solvents, disinfectants, and increased miscarriage risk cannot be ruled out.
Further research is recommended to clarify the reproductive risks associated with dental occupational exposures.