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Zinc supplementation and growth.

¹Department of Nutrition, Faculty of Medicine, University of Chile, Independencia 1027, Correo 7, Santiago, Chile. mruz@med.uchile.cl

Current Opinion in Clinical Nutrition and Metabolic Care

|October 21, 2006

Summary

Zinc supplementation shows limited benefits for healthy children

Area of Science:

Pediatric Nutrition
Micronutrient Research

Background:

Zinc is essential for child growth and development.
Maternal zinc status can impact fetal growth.
Understanding zinc's role in growth is crucial for public health.

Purpose of the Study:

To review the effects of zinc supplementation on infant and child growth.
To evaluate the impact of maternal zinc supplementation on intrauterine growth.

Main Methods:

Systematic review of existing studies on zinc supplementation and growth.
Analysis of data from trials involving infants, children, and pregnant women.

Main Results:

Zinc supplementation showed significant weight gain in some studies, but effects on height were less consistent.

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Multimicronutrient supplements including zinc also demonstrated positive effects on weight.

Interactions with other nutrients, like iron, can negate zinc's growth-promoting effects.

Maternal zinc supplementation yielded conflicting results on fetal growth.

Conclusions:

Zinc supplementation does not enhance growth in healthy, well-nourished children.
Beneficial effects on growth may occur in undernourished children with prolonged supplementation.
Growth is multifactorial, involving complex interactions of nutrients and other factors.
Further research is needed to understand these interactions and optimize zinc's impact on growth.