Related Experiment Video

Updated: Jul 19, 2026

Optimized Management of Endovascular Treatment for Acute Ischemic Stroke
09:21

Optimized Management of Endovascular Treatment for Acute Ischemic Stroke

Published on: January 18, 2018

Current concepts in the management of intracranial atherosclerotic disease

Robert D Ecker1, Elad I Levy, Eric Sauvageau

  • 1Department of Neurosurgery,School of Medicine and Biomedical Sciences, University at Buffalo, State University of New York, 14209, USA.

Neurosurgery
|October 21, 2006
PubMed

Insights

Symptomatic intracranial atherosclerotic disease poses a significant stroke risk. Advances in endovascular treatments offer new hope for managing this condition.

Area of Science:

  • Neurology
  • Vascular Neurology
  • Interventional Neurology

Background:

  • Medically refractory symptomatic intracranial atherosclerotic disease (ICAD) carries a poor prognosis.
  • The Warfarin-Aspirin Symptomatic Intracranial Disease study indicated a 13-14% risk of ipsilateral stroke at 1.8 years for patients with symptomatic ICAD.

Purpose of the Study:

  • To discuss recent clinical developments and concepts in the diagnosis and endovascular treatment of ICAD.
  • To highlight advancements in angioplasty, stenting, neuroimaging, and antithrombotic regimens for ICAD.

Main Methods:

  • Review of recent clinical developments and concepts.
  • Discussion of synergistic advances in neuroimaging and endovascular techniques.
  • Analysis of periprocedural and postprocedural antithrombotic strategies.

Main Results:

  • Intracranial angioplasty and stenting, coupled with advanced neuroimaging and antithrombotic protocols, are evolving treatment paradigms.
  • New models for diagnosis and successful endovascular management of ICAD are emerging.

Conclusions:

  • Significant progress is being made in the endovascular treatment of intracranial stenosis.
  • Improved diagnostic and therapeutic strategies are enhancing outcomes for patients with ICAD.

More Related Videos

Comprehensive Endovascular and Open Surgical Management of Cerebral Arteriovenous Malformations14:58

Comprehensive Endovascular and Open Surgical Management of Cerebral Arteriovenous Malformations

Published on: October 20, 2017

Related Concept Videos

Atherosclerosis III: Management01:26

Atherosclerosis III: Management

Management of atherosclerosis involves an integrated strategy encompassing pharmacological treatment, surgical interventions, lifestyle changes, and nutrition therapy to address the multifactorial nature of the disease.Pharmacological TherapyA cornerstone of atherosclerosis management is the use of pharmacological agents. Statins, such as atorvastatin, are pivotal in inhibiting HMG-CoA reductase, an enzyme that catalyzes an initial step in cholesterol synthesis in the liver. This reduction in...
Atherosclerosis IV: Nursing Management01:23

Atherosclerosis IV: Nursing Management

Nursing management for a patient with arteriosclerosis involves a comprehensive approach focusing on lifestyle modification, disease monitoring, education, and symptomatic care. Here is an overview of effective nursing strategies:Assessment and Monitoring: Initial and ongoing assessments are crucial. Nurses must document the patient's medical history, including any hypertension, diabetes, hyperlipidemia, and other cardiovascular diseases. Assessments also cover family history and lifestyle...
Aneurysm III: Interprofessional Care01:26

Aneurysm III: Interprofessional Care

Aneurysm management involves either conservative medical therapy or surgical intervention, depending on the size and symptoms of the aneurysm. Conservative management is generally reserved for smaller, asymptomatic aneurysms, while larger or symptomatic aneurysms often necessitate surgical repair.Conservative Medical TherapyFor small, asymptomatic aneurysms, particularly abdominal aortic aneurysms (AAA) less than 5.5 centimeters in diameter, conservative medical therapy is recommended. This...
Peripheral Artery Disease III: Interprofessional Care01:27

Peripheral Artery Disease III: Interprofessional Care

Peripheral Artery Disease (PAD) is characterized by narrowed arteries that diminish blood flow to the extremities. Effective management of PAD requires an interprofessional approach involving various healthcare professionals. The critical aspects of interprofessional care for PAD patients focus on risk factor modification, drug therapy, exercise therapy, nutrition therapy, critical limb ischemia care, and interventional radiology and surgical procedures.The primary treatment goal for PAD...
Coronary Artery Disease V: Interprofessional Care01:27

Coronary Artery Disease V: Interprofessional Care

Interprofessional care for coronary artery disease includes pharmacological therapy and revascularization procedures.Pharmacological therapy for Coronary Artery Disease (CAD) aims to manage symptoms, prevent complications, and improve patient outcomes through various classes of medications:Antiplatelet Agents:Aspirin and Clopidogrel: These medications inhibit platelet aggregation, preventing blood clots, which is crucial for avoiding heart attacks and strokes. Doctors often prescribe these...
Ischemic Stroke l: Introduction01:15

Ischemic Stroke l: Introduction

Ischemic stroke is an acute cerebrovascular condition in which blood flow to a brain region is suddenly interrupted, leading to tissue infarction. Neurons depend on continuous oxygen and glucose supply, so even brief reductions in perfusion cause energy failure, ionic imbalance, and irreversible injury. Ischemic strokes are classified into thrombotic and embolic types based on their underlying mechanisms.Thrombotic MechanismsThrombotic stroke develops when a clot forms within a cerebral artery.