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Related Experiment Videos

Infant position in neonates receiving mechanical ventilation.

A Balaguer1, J Escribano, M Roqué

  • 1Hospital Univ St. Joan Reus. Universitat Rovira i Virgili, Pediatrics, Sant Joan s/n, Reus, Catalonia, Spain. abalaguer@grupsagessa.com

The Cochrane Database of Systematic Reviews
|October 21, 2006
PubMed
Summary
This summary is machine-generated.

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Prone positioning slightly improves oxygenation in newborns on mechanical ventilation (MV). However, evidence for sustained clinical benefits or reduced complications from various body positions in neonates receiving MV is lacking.

Area of Science:

  • Neonatal intensive care
  • Respiratory physiology
  • Clinical trial methodology

Background:

  • Body positioning is utilized in intensive care to prevent complications like pressure ulcers and improve patient well-being.
  • Specific positions, such as prone, may enhance respiratory parameters in mechanically ventilated patients.
  • The benefits of various body positions for critically ill newborns requiring prolonged mechanical ventilation are not well-defined.

Purpose of the Study:

  • To evaluate the impact of different body positions on short-term respiratory outcomes in newborn infants receiving mechanical ventilation (MV).
  • To assess the effects of positioning on complications associated with prematurity in mechanically ventilated neonates.

Main Methods:

  • A systematic review of randomized or quasi-randomized clinical trials was conducted.

Related Experiment Videos

  • Searches included major databases (CINAHL, MEDLINE, EMBASE, CENTRAL) up to May 2006, and hand searches of conference proceedings.
  • Eleven trials involving 206 infants compared various positions, including prone, supine, and lateral, often using a crossover design.

    • Main Results:

    • Prone positioning showed a slight increase in arterial P02 (2.75-9.72 mm Hg) and improved hemoglobin oxygen saturation (1.18-4.36%) compared to supine.
    • A minor improvement in the frequency of desaturation episodes was observed in the prone position.
    • No statistically significant effects on other outcomes were found, and negative effects were not sufficiently studied.

    Conclusions:

    • The prone position offers a modest improvement in oxygenation for neonates on mechanical ventilation.
    • Current evidence does not confirm whether specific body positions provide sustained, clinically significant benefits or reduce complications in mechanically ventilated newborns.