Rome III: the new criteria

Area of Science:

• Gastroenterology
• Functional Gastrointestinal Disorders

Background:

• The Rome III criteria represent a significant advancement in the scientific understanding and classification of functional gastrointestinal disorders (FGIDs).
• This process involved over 15 years of dedicated work by international researchers.
• FGIDs lack specific biomarkers, necessitating consensus-based diagnostic criteria.

Purpose of the Study:

• To review the comprehensive process leading to the Rome III classification system.
• To detail the specific changes and advancements from the previous Rome II criteria.
• To outline the future activities and research directions of the Rome Foundation.

Main Methods:

• International collaboration involving 87 investigators from 17 countries.
• Development and publication of the Rome III book and a special issue in Gastroenterology (April 2006).
• Systematic review and consensus-building on FGID classification.

Main Results:

• Establishment of the Rome III classification system for FGIDs.
• Detailed comparison highlighting the evolution from Rome II to Rome III.
• Identification of key areas for future research and clinical application.

Conclusions:

• The Rome III criteria offer a scientifically validated framework for diagnosing and managing FGIDs.
• The collaborative international effort ensures global relevance and applicability.
• Continued research and updates are crucial for advancing FGID management.