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Related Concept Videos

Types of Genetic Transfer Between Organisms02:18

Types of Genetic Transfer Between Organisms

Genetic transfer occurs when genetic information is passed from one organism to another. It occurs via two mechanisms: vertical gene transfer and horizontal gene transfer. Vertical gene transfer occurs when genetic information is transferred from one generation to the next, which happens much more frequently than horizontal gene transfer. Both sexual and asexual reproduction are forms of vertical gene transfer, where one or more organisms pass some or all of their genome onto their progeny.
Types of Genetic Transfer Between Organisms02:18

Types of Genetic Transfer Between Organisms

Genetic transfer occurs when genetic information is passed from one organism to another. It occurs via two mechanisms: vertical gene transfer and horizontal gene transfer. Vertical gene transfer occurs when genetic information is transferred from one generation to the next, which happens much more frequently than horizontal gene transfer. Both sexual and asexual reproduction are forms of vertical gene transfer, where one or more organisms pass some or all of their genome onto their progeny.
Horizontal Gene Transfer01:27

Horizontal Gene Transfer

Horizontal gene transfer (HGT) is a process where genetic material moves between organisms within the same generation, unlike vertical gene transfer, which occurs from parent to offspring. HGT plays a crucial role in microbial evolution, adaptation, and survival, particularly in shared environments like the human gut.Mobile genetic elements such as plasmids, prophages, integrons, insertion sequences, and transposons facilitate this process. HGT occurs through three primary mechanisms:...
Genome Size and the Evolution of New Genes03:21

Genome Size and the Evolution of New Genes

While every living organism has a genome of some kind (be it RNA, or DNA), there is considerable variation in the sizes of these blueprints. One major factor that impacts genome size is whether the organism is prokaryotic or eukaryotic. In prokaryotes, the genome contains little to no non-coding sequence, such that genes are tightly clustered in groups or operons sequentially along the chromosome. Conversely, the genes in eukaryotes are punctuated by long stretches of non-coding sequence.
Viral Recombination00:57

Viral Recombination

Cells are sometimes infected by more than one virus at once. When two viruses disassemble to expose their genomes for replication in the same cell, similar regions of their genomes can pair together and exchange sequences in a process called recombination. Alternatively, viruses with segmented genomes can swap segments in a process called reassortment.
Transduction01:16

Transduction

Among the three main modes of HGT—transformation, conjugation, and transduction—transduction is unique in that it is mediated by bacteriophages, or bacterial viruses.Transduction occurs in two ways. Generalized transduction occurs during the lytic cycle of a bacteriophage infection. In this process, bacteriophages infect bacterial cells, replicate within them, and ultimately cause cell lysis, releasing newly assembled virions. Occasionally, random fragments of the bacterial genome are...

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Related Experiment Video

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Detection of Horizontal Gene Transfer Mediated by Natural Conjugative Plasmids in E. coli
06:56

Detection of Horizontal Gene Transfer Mediated by Natural Conjugative Plasmids in E. coli

Published on: March 24, 2023

Rapid disease emergence through horizontal gene transfer between eukaryotes.

Ian R Sanders1

  • 1Department of Ecology and Evolution, University of Lausanne, 1015 Lausanne, Switzerland. ian.sanders@unil.ch

Trends in Ecology & Evolution
|October 24, 2006
PubMed
Summary

Horizontal gene transfer in eukaryotes is not well understood. A recent fungal gene transfer rapidly increased wheat pathogen virulence, highlighting disease emergence mechanisms and questioning fungal incompatibility barriers.

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Area of Science:

  • Evolutionary biology
  • Genetics
  • Plant pathology

Background:

  • The evolutionary impact and prevalence of horizontal gene transfer (HGT) among eukaryotes, particularly fungi, are not fully elucidated.
  • Understanding HGT mechanisms is crucial for comprehending rapid evolutionary changes and the emergence of novel traits.

Purpose of the Study:

  • To investigate a recent instance of horizontal gene transfer between fungal species.
  • To determine the role of this gene transfer in the acquisition of virulence against wheat.
  • To explore the implications for fungal evolution and disease emergence.

Main Methods:

  • Comparative genomics analysis of fungal species.
  • Phylogenetic analysis to trace gene origins.
  • Experimental validation of gene function and virulence.

Main Results:

  • A specific gene was identified as recently transferred between two fungal species.
  • The transferred gene conferred a significant increase in virulence on wheat in the recipient fungus.
  • Evidence suggests fungal incompatibility barriers may be more permeable than previously assumed.

Conclusions:

  • Recent HGT can rapidly equip pathogens with enhanced virulence, facilitating sudden disease emergence.
  • This study provides a model for understanding how pathogens evolve and adapt.
  • The findings challenge existing notions about reproductive isolation and gene flow in fungi.