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A novel human multi-locus DNA family detected by pJU78 (DF31)
F Peinemann1, D N Cooper, K H Grzeschik
1Institut für Humangenetik der Universität, Göttingen, Federal Republic of Germany.
Human Genetics
|February 1, 1991
Abstract:
pJU78 is a 2.9-kb cloned human DNA segment derived from Xq24-q26. When used as a hybridization probe, it detects some 25 related sequences dispersed over the genome, including several autosomes and the X and Y chromosomes. Several pJU78-related sequences were chromosomally allocated and five different restriction fragment length polymorphisms detected and partially characterized in population and family studies. This sequence family was not found in non-primate species. The sequence appears to lack CpG-island character and is not detectably expressed in a variety of human tissues.