Mixed clear cell and endometrioid carcinoma arising in parietal endometriosis
Kais Razzouk1, Horace Roman, Isabella Chanavaz-Lacheray
1Department of Gynecology and Obstetrics, University Hospital, Rouen, France.
Aim:
We report a case of a mixed clear cell and endometrioid carcinoma arising in parietal endometriosis.
Methods:
A 46-year-old woman presented a second recurrence of parietal endometriosis. An extensive surgical resection of the tumor was then carried out.
Results:
Histological analysis revealed heterogeneous tissues including clear cell and endometrioid carcinoma fields arising from a large benign endometriosis lesion. Despite chemotherapy, the patient died 6 months after the diagnosis.
Conclusions:
Clear cell carcinoma and endometrioid carcinoma have been rarely found in parietal endometriosis. Clinicians should learn to suspect a cancerous transformation of a parietal endometriosis, when rapid recurrence and extensive development are observed.
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