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Coxiella burnetii antigens may induce resistance to tumour growth
N K Tokarevich1, A M Maligin, T A Kramskaya
1Pasteur Institute of Epidemiology and Microbiology, Leningrad, U.S.S.R.
Acta Virologica
|August 1, 1990
Abstract:
Coxiella burnetii antigens stimulate the defence against growth of hepatoma 22a cells. The antigen-stimulated mice survived longer, they considerably later developed palpable tumours and showed a retarded tumour growth. The enhanced resistance to tumour growth may be explained by at least 2 interrelated phenomena; namely by the induction of interferon-like activity and an increased NK cell activity.