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Dynamic atypical optic nerve coloboma associated with transient macular detachment
Stephen L Perkins1, Dennis P Han, John R Gonder
1Department of Ophthalmology, Medical College of Wisconsin, Milwaukee, Wisconsin, USA.
Transactions of the American Ophthalmological Society
|October 24, 2006
Summary
Atypical optic nerve colobomas can dynamically change with associated maculopathy. Spontaneous resolution of macular detachment occurred with concurrent, evolving optic nerve coloboma changes in three patients.
Area of Science:
- Ophthalmology
- Retinal diseases
- Optic nerve disorders
Background:
- Macular schisis or detachment commonly occurs with optic pits or colobomas.
- Spontaneous resolution of maculopathy is known, but optic nerve coloboma changes are not well-documented.
Observation:
- Three patients with macular detachment and atypical optic nerve colobomas were studied.
- Dynamic optic nerve changes were observed over several months.
- Fundus photography and fluorescein angiography documented optic nerve and macular changes.
Findings:
- Macular detachments spontaneously resolved in all three patients.
- Concurrent, dynamic changes in atypical optic nerve colobomas were observed.
- Visual acuity improved significantly after spontaneous resolution.
Implications:
- Fluctuating optic nerve changes can accompany atypical optic nerve coloboma and maculopathy.
- Observation may be appropriate before intervention for maculopathy with unclear optic nerve coloboma.
- This study highlights the dynamic nature of optic nerve colobomas in relation to maculopathy.
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