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Updated: Jul 19, 2026

Auricular Acupressure as an Adjuvant Treatment for Wheezing in Stable Chronic Obstructive Pulmonary Disease
Published on: May 10, 2024
[Wheezing and cough related to congenital airway abnormalities in young infants]
M van Veen1, W A F Balemans, J A Schipper
1St Antonius Ziekenhuis, afd Kindergeneeskunde, Nieuwegein. m.vanveen@erasmusmc.nl
Insights
Infantile wheezing unresponsive to bronchodilators may signal rare airway malformations. Early diagnosis of bronchomalacia and tracheomalacia is crucial for infants with persistent respiratory symptoms.
Area of Science:
- Pediatric Pulmonology
- Medical Imaging
- Congenital Disorders
Background:
- Broncho- and tracheomalacia are rare congenital airway disorders.
- These conditions can present with persistent wheezing and coughing in infants.
- Symptoms often mimic viral infections but are unresponsive to standard treatments.
Observation:
- Two infants presented with severe, persistent wheezing and respiratory distress shortly after birth.
- Diagnostic workup included chest X-ray, bronchoscopy, and CT angiogram.
- Findings revealed isolated left main stem bronchus malacia in one infant and tracheomalacia due to aortic arch compression in the other.
Findings:
- Bronchomalacia: Isolated malacia of the left main stem bronchus.
- Tracheomalacia: Caused by extrinsic compression from a right descending aortic arch.
- Both cases presented with severe respiratory distress unresponsive to bronchodilators.
Implications:
- Airway malformations like bronchomalacia and tracheomalacia should be considered in infants with unexplained, persistent respiratory symptoms.
- Prompt diagnosis through bronchoscopy and imaging is vital for appropriate management.
- Early identification can prevent severe respiratory distress and improve infant outcomes.
Abstract:
Two girls developed symptoms of wheezing which started shortly after birth. The symptoms did not respond to bronchodilators. At the age of 5 months, the first infant developed severe respiratory distress with decreased left-sided breathing sounds on auscultation. The chest X-ray showed left-sided hyperinflation. Bronchoscopy revealed isolated malacia of the left main stem bronchus. The second patient, who had a history ofcor vitium, was referred to a paediatric pulmonologist in an academic hospital for chronic coughing and wheezing. Bronchoscopy and CT angiogram, performed at the age of 14 months, revealed tracheal malacia due to compression from a right descending aortic arch. Broncho- and tracheomalacia are disorders which may rarely result in severe respiratory distress. These disorders should be considered when unexplained symptoms of wheezing or coughing are present in young infants, especially if the symptoms start shortly after birth and persist without signs of viral infection.
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