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A Model of Acute Lung Injury Following Visceral Ischemia-Reperfusion by Supra-Coeliac Aortic Cross Clamping in Rats
Published on: August 15, 2025
[Traumatic rupture of the thoracic aorta]
1Department of Cardiovascular Surgery, Shonan-Kamakura General Hospital, Kamakura, Japan.
Kyobu Geka. the Japanese Journal of Thoracic Surgery
|October 25, 2006
Summary
Traumatic aortic rupture is a life-threatening condition. Hypothermic circulatory arrest offers an effective treatment for hemodynamically unstable patients, improving survival rates.
Area of Science:
- Cardiovascular Surgery
- Trauma Surgery
- Emergency Medicine
Context:
- Traumatic aortic rupture presents a significant challenge in emergency medicine.
- Hemodynamic instability is a common complication, increasing mortality risk.
Purpose:
- To review the efficacy of hypothermic circulatory arrest in managing traumatic aortic rupture.
- To evaluate outcomes in hemodynamically unstable patients undergoing emergent surgical repair.
Summary:
- Eight patients with traumatic rupture of the thoracic aorta, primarily caused by traffic accidents, underwent emergent surgical repair within 12 hours using hypothermic circulatory arrest.
- All injuries were located in the aortic isthmus.
Impact:
- Hypothermic circulatory arrest demonstrated effectiveness, with a 7/8 survival rate, free from neurological complications.
- The study highlights the critical importance of managing concurrent visceral bleeding for successful outcomes in traumatic aortic rupture cases.
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