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Published on: March 2, 2020
[Study on the TLC-SERS of sulfamethoxazole]
Jin-Zhi Zhang1, Yuan Wang, Xiang-Ming Chen
1Department of Physics, North China University of Technology, Beijing 100041, China.
Abstract:
The spectra of sulfamethoxazole, the efficient ingredient of sulfanilamide-like medicine, were investigated by combining the TLC and FT-Raman spectroscopy using the surface enhanced Raman spectroscopy technique. The result indicatesthat the main vibrant characteristic spectral band can be obtained by TLC in a samples of just about 1 microg. The difference between the compound sulfamethoxazole and the corresponding spectra picture is analyzed. The analysis shows that the method of combining TLC and FT-Raman spectroscopy by the SERS is practical and advantageous in the highly sensitive measurement of the chemical ingredient in medicine.
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