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Updated: Jul 19, 2026

08:20
Murine Distal Colostomy, A Novel Model of Diversion Colitis in C57BL/6 Mice
Published on: July 12, 2018
[A rare complication of colostomy]
Camelia Chifu1, C Diaconu, Lidia Andriescu
1Clinica III Chirurgie, Spitalul de Urgente Sf Spiridon, Iaşi. cchifu2000@yahoo.fr
Summary
A patient with a history of rectal cancer surgery developed a severe abdominal infection and colostomy complications. Aggressive treatment and surgery led to recovery, with plans for further colostomy reversal.
Area of Science:
- Gastroenterology
- Surgical Oncology
- Infectious Diseases
Background:
- A 64-year-old female patient with a prior Miles operation for rectal cancer presented with complications.
- The patient had a history of rectal cancer treated with a Miles operation six years prior to this admission.
Observation:
- The patient developed a severe infection around her left colostomy, initially localized but progressing.
- The infection evolved into extensive necrotizing fasciitis of the abdomen, colostomy dehiscence, and severe sepsis.
Findings:
- Repeated surgical interventions, including a transverse colostomy to rest the infected left colostomy, were performed.
- Aggressive medical management alongside surgical procedures resulted in wound healing and a successful redo of the left colostomy.
Implications:
- This case highlights the potential for severe complications following ostomy surgery, even years later.
- Prompt and aggressive multidisciplinary management is crucial for favorable outcomes in complex peristomal infections and sepsis.
- Further surgical intervention may be required to manage complications and restore quality of life.
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