Related Experiment Video
Updated: Jul 19, 2026
A Coregistered Ultrasound and Photoacoustic Imaging Protocol for the Transvaginal Imaging of Ovarian Lesions
Published on: March 3, 2023
[Transvaginal color doppler ultrasonography and CA125 detection in surveillance of ovarian malignant tumors after
Hui Zeng1, Xiao-Qing Pei, Dan-Miao Zheng
1State Key Laboratory of Oncology in South China, Guangzhou, Guangdong, 510060, P. R. China. gzzeng@163.com
Background & Objective:
Although transvaginal ultrasonography color Doppler flow imaging (TV-CDFI) has been widely applied in ultrasonography diagnosis, studies on TV-CDFI combined with a serum tumor marker CA125 detection in the surveillance of ovarian malignant tumors after operation are few. This study was to evaluate TV-CDFI combined with CA125 detection in the surveillance of ovarian malignant tumors after operation.
Methods:
Sixty-two cases of ovarian malignant tumors after operation were examined by TV-CDFI. The level of CA125 was measured, and the results were evaluated compared with pathologic findings. The diagnostic sensitivity, specificity, and accuracy were calculated.
Results:
The diagnostic sensitivity of TV-CDFI or CA125 alone was 84.6% and 65.4%; the specificity was 88.9% and 66.7%; the accuracy was 87.1% and 66.1%. While the diagnostic sensitivity of TV-CDFI combined with CA125 was 92.3%, the specificity was 88.9%, and the accuracy rate rose to 90.3% (P<0.05).
Conclusion:
The diagnostic accuracy for recurrent ovarian malignant tumors is improved by TV-CDFI combined with CA125, which is more helpful in the surveillance of recurrent ovary malignant tumors than TV-CDFI alone.
