Image reconstruction for positron emission tomography using fuzzy nonlinear anisotropic diffusion penalty
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Updated: Jul 19, 2026

Advanced Diffusion Imaging in The Hippocampus of Rats with Mild Traumatic Brain Injury
Published on: August 14, 2019
Hongqing Zhu1, Huazhong Shu, Jian Zhou
1Laboratory of Image Science and Technology, Department of Computer Science and Engineering, Southeast University, Nanjing, People's Republic of China. hqzhu@seu.edu.cn
Abstract:
Iterative algorithms such as maximum likelihood-expectation maximization (ML-EM) become the standard for the reconstruction in emission computed tomography. However, such algorithms are sensitive to noise artifacts so that the reconstruction begins to degrade when the number of iterations reaches a certain value. In this paper, we have investigated a new iterative algorithm for penalized-likelihood image reconstruction that uses the fuzzy nonlinear anisotropic diffusion (AD) as a penalty function. The proposed algorithm does not suffer from the same problem as that of ML-EM algorithm, and it converges to a low noisy solution even if the iteration number is high. The fuzzy reasoning instead of a nonnegative monotonically decreasing function was used to calculate the diffusion coefficients which control the whole diffusion. Thus, the diffusion strength is controlled by fuzzy rules expressed in a linguistic form. The proposed method makes use of the advantages of fuzzy set theory in dealing with uncertain problems and nonlinear AD techniques in removing the noise as well as preserving the edges. Quantitative analysis shows that the proposed reconstruction algorithm is suitable to produce better reconstructed images when compared with ML-EM, ordered subsets EM (OS-EM), Gaussian-MAP, MRP, TV-EM reconstructed images.
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