Related Experiment Video
Updated: Jul 19, 2026

A Purification and In Vitro Activity Assay for a (p)ppGpp Synthetase from Clostridium difficile
Published on: November 3, 2018
[The PQQ-dehydrogenases. A novel example of bacterial quinoproteins]
Marcos Flores-Encarnación1, Mariano Sánchez-Cuevas, Felipe Ortiz-Gutiérrez
1Departamento de Ciencias de la Salud, Facultad de Medicina, Universidad Popular Autónoma del Estado de Puebla. mflores31@hotmail.com
Abstract:
The word "quinoprotein" describes four groups of different enzymes which have cofactors containing o-quinones. Pyrrolo-quinoline quinone (PQQ) is not covalently attached. PQQ is the cofactor of several quinoprotein bacterial dehydrogenases including glucose dehydrogenase (G-DH), alcohol dehydrogenase (A-DH) and aldehyde dehydrogenase (AL-DH). These dehydrogenases are located in the periplasm of Gram-negative bacteria. This report summarises the structural properties of quinoprotein dehydrogenases, such as the biological functions and biotechnological aspects more important.
Related Concept Videos
Gene Regulation in Microbial Communities: Quorum Sensing
Oxidation of Phenols to Quinones
o-hydroxy phenols are oxidized to o-quinones and p-hydroxy phenols to p-quinones. Such redox reactions involve the transfer of two electrons and two protons. The reversible redox property is crucial in...
Bacterial Signaling
Anoxygenic Photosynthesis
Electron Transport Chain: Complex III and IV
Protein Import into the Peroxisomes
Peroxisomal Protein Import:
Peroxisomes lack the genetic machinery required to code for their own proteins. Hence, most peroxisomal membrane, lumenal and transmembrane proteins are synthesized in the cytoplasm or ER and transported to the peroxisome...

