Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

Leucocyte cellular adhesion molecules.

K Yong1, A Khwaja

  • 1Department of Haematology, University College and Middlesex School of Medicine, London, UK.

Blood Reviews
|December 1, 1990
PubMed
Summary
This summary is machine-generated.

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Haematopoietic stem cell mobilisation followed by high-dose chemotherapy and autologous stem cell transplantation for patients with sickle cell disease and myeloma.

British journal of haematology·2023
Same author

Correction: PI3-kinase/Akt is constitutively active in primary acute myeloid leukaemia cells and regulates survival and chemoresistance via NF-kB, MAPkinase and p53 pathways.

Leukemia·2021
Same author

Evaluation of estimated glomerular function (eGFR) versus creatinine clearance (CrCl) to predict acute kidney injury when using zoledronate for the treatment of osteoporosis.

Osteoporosis international : a journal established as result of cooperation between the European Foundation for Osteoporosis and the National Osteoporosis Foundation of the USA·2021
Same author

Plasma metabolome alteration in dairy cows with left displaced abomasum before and after surgical correction.

Journal of dairy science·2021
Same author

Author Correction: Mir142 loss unlocks IDH2<sup>R140</sup>-dependent leukemogenesis through antagonistic regulation of HOX genes.

Scientific reports·2021
Same author

Acute kidney injury: prevention, detection, and management. Summary of updated NICE guidance for adults receiving iodine-based contrast media.

Clinical radiology·2021
Same journal

Treating large B-cell lymphoma: Current strategies and unmet needs across community and academic settings.

Blood reviews·2026
Same journal

MRD in multiple myeloma: Moving from "minimal" to "measurable".

Blood reviews·2026
Same journal

PRISMA-based systematic review on iron stores in repeat blood donors.

Blood reviews·2026
Same journal

Artificial intelligence applications in thrombotic thrombocytopenic Purpura: A systematic review of diagnostic, risk stratification, and prognostic models.

Blood reviews·2026
Same journal

Antibacterial, antifungal and antiviral prophylaxis and vaccination strategies in adult patients with acute myeloid and promyelocytic leukemia: An expert panel consensus from the GIMEMA group.

Blood reviews·2026
Same journal

The Lebanese national patient blood management guidelines: A new page in the medical practice.

Blood reviews·2026
See all related articles

Leukocytes use adhesion receptors like integrins for cell interactions vital to immunity and inflammation. This review focuses on leukocyte integrins and their roles in immune responses and cell trafficking.

Area of Science:

  • Immunology and Cell Biology
  • Molecular and Cellular Medicine

Background:

  • Leukocytes express adhesion receptors mediating crucial cell-cell and cell-matrix interactions.
  • These interactions regulate haemopoiesis, thymocyte maturation, leukocyte traffic, and inflammatory responses.

Purpose of the Study:

  • To review adhesion receptors found on leukocytes.
  • To emphasize the critical role of leukocyte integrins in immune and inflammatory processes.

Main Methods:

  • Literature review focusing on adhesion receptor families.
  • Detailed examination of the structure and function of leukocyte integrins (CD11/CD18 family).

Main Results:

  • Identified several families of leukocyte adhesion receptors: integrins, immunoglobulin superfamily, and selectins.

Related Experiment Videos

  • Highlighted the leucocyte integrin family, including LFA-1, Mac-1, and p150,95, and their involvement in immune responses.
  • Discussed other integrin subfamilies (VLA, cytoadhesins) and selectins (LAM-1, ELAM-1, GMP-140) and their functions.

    • Conclusions:

    • Adhesion receptors are fundamental to leukocyte function in immunity and inflammation.
    • Leukocyte integrins are key players in immune cell interactions and trafficking.
    • Further research into these receptors can advance understanding of immune and inflammatory diseases.