Related Experiment Video
Updated: Jul 19, 2026

Cox-Maze IV Procedure Concomitant with Valvular Surgery In Situs Inversus Dextrocardia: A Single-Center Experience in China
Published on: February 11, 2022
Impact of maze and concomitant mitral valve surgery on clinical outcomes
1Heart, Lung and Vascular Surgical Centre, Mount Elizabeth Medical Centre, Singapore. javas@magix.com.sg
Abstract:
We evaluated the usefulness of the maze procedure among patients with atrial fibrillation undergoing mitral valve surgery. Seven matched-controlled and four randomized trials were identified from Medline English language papers (1995 to 2005). After 2 to 8 years of follow-up in matched-controlled studies, odds ratio and 95% confidence interval (CI) for atrial fibrillation free, embolic events free, and long-term survival for those treated with maze were 12.51 (95% CI: 9.18 to 17.03), 9.35 (95% CI: 5.11 to 17.13), and 2.27 (95% CI: 1.21 to 4.27), respectively. Correspondingly, after 1 to 1.5 years of follow-up in randomized trials, they were 9.01 (95% CI: 4.21 to 19.3), 5.19 (95% CI: 0.50 to 53.6), and 0.49 (95% CI: 0.12 to 1.93), respectively. The addition of the maze procedure to mitral valve surgery was more likely to maintain patients in sinus rhythm and may lower embolic events, including stroke, but did not necessarily improve long-term survival.
Related Concept Videos
Mitral Stenosis III: Medical Management
Mitral Stenosis II: Clinical features and Diagnostic Tests
Mitral Valve Prolapse II: Assessment and Management
Mitral Stenosis I: Introduction
Mitral Regurgitation III: Medical Management
Mitral Stenosis IV: Nursing Management

