The fear of necrotizing enterocolitis versus achieving optimal growth in preterm infants--an opinion

Orna Flidel-Rimon1, David Branski, Eric S Shinwell

  • 1Department of Neonatology, Kaplan Medical Center, Rehovot, Israel.

Insights

Early enteral feeding for very-low-birthweight (VLBW) infants is crucial for growth. Concerns about necrotizing enterocolitis (NEC) should not impede timely nutritional support, as evidence supports early and rapid advancement of feeds.

Area of Science:

  • Neonatology
  • Pediatric Nutrition
  • Infant Growth

Background:

  • Very-low-birthweight (VLBW) infants experience significant growth delays.
  • Current nutritional strategies often involve a combination of enteral and parenteral nutrition.
  • Fear of necrotizing enterocolitis (NEC) leads to delayed enteral feeding in VLBW infants.

Purpose of the Study:

  • To re-evaluate the nutritional strategies for VLBW infants.
  • To challenge the traditional approach of delaying enteral feeds due to NEC concerns.
  • To emphasize the importance of optimizing growth in VLBW infants.

Main Methods:

  • Review of current evidence on enteral and parenteral nutrition in VLBW infants.
  • Analysis of the impact of feeding strategies on infant growth.
  • Assessment of the risks and benefits associated with early versus delayed enteral feeding.

Main Results:

  • Early enteral feeding, advanced at rates of 20-35 ml/kg/d, demonstrates significant benefits for VLBW infants.
  • Delayed enteral feeding, driven by NEC fears, contributes to marked growth delay.
  • Optimizing enteral nutrition is key to improving growth outcomes.

Conclusions:

  • The primary concern guiding nutritional strategies for VLBW infants should be inadequate growth, not the fear of NEC.
  • Early and progressive enteral feeding should be prioritized.
  • Revising current feeding protocols can enhance growth and development in VLBW infants.
Abstract