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Updated: Feb 9, 2026
06:42
Use of the Scissor-Type Knife During the Peroral Endoscopy Myotomy Procedure for the Treatment of Achalasia
Published on: March 3, 2023
3.6K
[Gamma knife treatment for pituitary prolactinomas]
Zhi-ming Ma1, Bin Qiu, Yong-hong Hou
1Department of Neurological Surgery, Xiangya Hospital, Central South University, Changsha 410008, China. mazhiming64@yahoo.com.cn
Summary
Gamma knife radiosurgery offers a 100% tumor growth control rate for prolactinomas. This treatment achieved 40% endocrinological remission in selected patients, making it a viable primary option, especially for pituitary microadenomas.
Area of Science:
- Neurosurgery
- Radiation Oncology
- Endocrinology
Context:
- Prolactinomas are the most common pituitary tumors.
- Gamma knife radiosurgery (GKRS) is a minimally invasive treatment option.
- Evaluating GKRS efficacy for prolactinomas is crucial for treatment selection.
Purpose:
- To assess the effectiveness of gamma knife radiosurgery in managing prolactinomas.
- To determine tumor control, endocrinological remission, and complication rates following GKRS.
Summary:
- Eighty-nine patients with prolactinomas underwent GKRS, with 51 followed for 6-108 months (mean 37 months).
- Tumor doses ranged from 18-35 Gy (margin) and 36-60 Gy (maximum).
- Results showed 100% tumor growth control, 40% endocrinological remission, and 17.6% incidence of hypopituitarism.
Impact:
- GKRS demonstrates high efficacy in controlling prolactinoma growth.
- It represents a potential primary treatment for selected prolactinomas, particularly microadenomas.
- Understanding complication rates is essential for patient counseling and management.
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