Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

Clear cell basal cell carcinoma.

T M Starink1, C E Blomjous, T J Stoof

  • 1Department of Dermatology, Academic Hospital, Free University, Amsterdam, The Netherlands.

Histopathology
|November 1, 1990
PubMed
Summary
This summary is machine-generated.

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Node negative colorectal cancer patients: assesment of high-risk features on recurrence.

Pathology, research and practice·2020
Same author

Extensive Persistent Panniculitis in the Context of Dermatomyositis.

Journal of clinical rheumatology : practical reports on rheumatic & musculoskeletal diseases·2019
Same author

Convective-Dispersion Modeling in 3D Contrast-Ultrasound Imaging for the Localization of Prostate Cancer.

IEEE transactions on medical imaging·2018
Same author

High-risk human papillomavirus detection in self-sampling compared to physician-taken smear in a responder population of the Dutch cervical screening: Results of the VERA study.

Preventive medicine·2017
Same author

Prognostic implications of occult nodal tumour cells in stage I and II colon cancer: The correlation between micrometastasis and disease recurrence.

European journal of surgical oncology : the journal of the European Society of Surgical Oncology and the British Association of Surgical Oncology·2017
Same author

A Randomised Controlled Trial of Consent Procedures for the Use of Residual Tissues for Medical Research: Preferences of and Implications for Patients, Research and Clinical Practice.

PloS one·2016
Same journal

Flat epithelial atypia of the breast: a pragmatic, context-integrated diagnostic framework within a biological continuum.

Histopathology·2026
Same journal

Myxoid neoplasms with MAP3K kinase fusion: a study of 39 cases.

Histopathology·2026
Same journal

TROP2 immunoreactivity in pulmonary large cell neuroendocrine carcinoma.

Histopathology·2026
Same journal

Malignant adenomyoepithelioma of the breast: seven cases illustrating morphological diversity and diagnostic challenges.

Histopathology·2026
Same journal

A CRX-positive RB1-deficient bone tumour with a retinoblastoma-like DNA methylation profile.

Histopathology·2026
Same journal

Perivascular epithelioid cell tumours of the genitourinary tract: clinicopathological features and molecular landscape.

Histopathology·2026
See all related articles

A rare clear cell basal cell carcinoma (BCC) variant was identified on the abdomen. Histology revealed clear cells with pagetoid infiltration, linked to a deeper nodular BCC, confirming its nature.

Area of Science:

  • Dermatopathology
  • Oncology

Background:

  • Basal cell carcinoma (BCC) is the most common human malignancy.
  • Clear cell variants of BCC are exceptionally rare, posing diagnostic challenges.

Observation:

  • A case of superficial BCC with clear cell features presented as a crusted abdominal eruption.
  • Histopathology showed a proliferation of clear cells beneath an atrophied epidermis with pagetoid infiltration.
  • A connection to a deeper nodular BCC confirmed the diagnosis.

Findings:

  • Immunohistochemistry and electron microscopy confirmed epithelial origin.
  • The clear cell morphology resulted from membrane-lacking, electron-lucent cytoplasmic vacuoles.

Implications:

  • This case expands the histopathological spectrum of basal cell carcinoma.

Related Experiment Videos

  • Understanding the clear cell variant aids in accurate diagnosis and management of BCC.